B12 institute is an independent non-profit institute

B12 Institute is an independent non-profit Treatment- and Carecenter (ZBC/polikliniek) with an independent WTZi-beschikking (Admission of Health care institutions Act licence) issued by the Dutch Ministry of Health, Welfare and Sport,  providing medical-specialist care. The institute follows an independent policy, for which it takes full responsibility. It has no commitments or ties with commercial parties or other clinics.

B12 Institute is the first independent expertise center on diagnosis and treatment of vitamin B12 and folate deficiency in Europe.

Renewed awareness of vitamin B12 and folate deficiency effects made clear that establishing a specialized diagnose and treatment center was necessary.

AGB-code B12 Institute: 2222-0908

B12 Research Foundation 

B12 Research Foundation functions as a separate entity within B12 Institute.


B12 Institute has the mission to optimize the diagnosis and treatment of patients with vitamin B12 and folate deficiency; its aim is to prevent under- and overtreatment. We believe our policy will bring about lower health care costs.

We will achieve our mission by:

  • setting up an independent expertise center for diagnosis and treatment of vitamin B12 and folate deficiency patients.
  • by way of our B12 Research Foundation: international cooperation with scientists and exchanging scientific data and good practices.
  • Informing doctors and patients.

B12 Institute Components  

  • diagnostics
  • treatment
  • research (by means of B12 Research Foundation, financed separately)
  • education


B12 Institute and B12 Research Foundation work closely together with international researchers, including researchers at Rotterdam Erasmus Medical Center, Clinical Chemistry Department and University of California, Department of Nutrition. Representatives of these universities are also Medical and Scientific Advisory Board (MWAR) and B12 Research Foundation members. Like us, they are specialists in the field of vitamin B12, one-carbon metabolism and related co-factors with a major influence on people’s health.